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Singulair (montelukast), a leukotriene receptor antagonist, is primarily used to prevent wheezing, difficulty breathing, chest tightness, and coughing caused by asthma in adults and children. A Heading Level 2 The following adverse responses have actually been identified during post-approval usage of Singulair Singulair was first approved can i buy xyzal in 1998 for asthma in adults, but was later approved for children in 2000. Until last year — when it wasn’t. 5 % in placebo-treated patients, over the double-blind therapy moments; this reflects a mean difference of 12. Its patent exprired, and Merck, understandably, applied tot he FDA to sell the drug over-the-counter (OTC) to adults for the temporary relief of symptoms due to hay fever or other upper respieatory allergies nasal congestion, runny nose, itchy,. Another major difference between these two medications is the availability of each medication. 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